Expresión de búsqueda: ALKB HOMOLOG 8, TRNA METHYLTRANSFERASE 
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Descriptor Inglés:   AlkB Homolog 8, tRNA Methyltransferase 
Descriptor Español:   Homólogo 8 de AlkB ARNt Metiltransferasa 
Descriptor Portugués:   Homólogo AlkB 8 da RNAt Metiltransferase 
Sinónimos Inglés:   Alkylated DNA Repair Protein Alkb Homolog 8
Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH8
S-Adenosyl-L-Methionine-Dependent tRNA Methyltransferase ABH8
tRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH8
Probable Alpha Ketoglutarate Dependent Dioxygenase ABH8
S Adenosyl L Methionine Dependent tRNA Methyltransferase ABH8  
Categoría:   D08.811.682.690.416.139.984
D08.811.913.555.500.925.500
Definición Inglés:   A dioxygenase and alkylation repair homolog that catalyzes the methylation of 5-carboxymethyl URIDINE to 5-methylcarboxymethyl uridine at the wobble position of the ANTICODON loop in TRANSFER RNA (tRNA) via its methyltransferase domain. It has a preference for tRNA (ARGININE) and tRNA (GLUTAMATE), and does not bind tRNA (LYSINE). 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   56502 
Identificador Único:   D000071503 

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